Carcinogenesis, Teratogenesis & Mutagenesis ›› 2005, Vol. 17 ›› Issue (1): 54-55.doi: 10.3969/j.issn.1004-616x.2005.01.018

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Acute Toxicity and Genetic Toxicity Tests of Solanum Nigrum L Juice

LAI Ya-hui;MA Zhong-chun;YAN Hui-yi;et al   

  1. Medical College of Beihua University,Jilin 132013,China
  • Received:2004-08-20 Revised:2004-10-25 Online:2005-01-30 Published:2005-01-30
  • Contact: LAI Ya-hui

Abstract: BACKGROUND & AIM: To study the acute toxicity and genetic toxicity of Solanum nigrum L juice. MATERIAL AND METHODS: Acute toxicity test of mice ,Ames test, micronucleus rest of bone marrow PCE cell in mice, sperm shape abnormality test of mice. RESULTS: Solanum Nigrum L Juice was a substance with no toxicity according to the acute toxicity. The results of genetic toxicity tests were all negative, including Ames test ,micronucleus rest and sperm shape abnormality test. CONCLUSION: Solanum Nigrum L Juice was a substance with no toxicity and had no genetic toxicity in this test.

Key words: Solanum nigrum L juice, genetic toxicity, Ames test, micronucleus test, sperm shape abnormality test